Fear Conditioning System Reference (some): Zhongshan Institute for Drug Discovery, Tongji Medical College, Huazhong University of Science and Technology, Zhejiang Institute of Natural Medicine, Hangzhou Seventh People's Hospital, West China Hospital, Sichuan University
The Grip Strength Meter is widely used to evaluate the motor function in rodents such as rats or mice. By determining the maximum force displayed by the rodent, it acts as a good tool in studying neuromuscular functions in rodents. BioMed’s Grip Strength Meter comes with the analysis software which can calculate the data automatically, makes it very convenient for biological statistics.
The Activity Hole Board Test is used to study the behavior of rodent when facing a new environment (protruding into the hole). By detecting the spontaneous activity of mice/rats, it can be used for new drug screening, pharmacology, nervous system research and Central nervous excitation and inhibition etc.Our IR Activity Hole Board Test consist of analysis software, video monitoring system and IR detection system. Rodent movement trajectory, distance, speed and time can be achieved and analyzed by our software. IR detection system is used to record the number of protruding, initial time, duration and total time of protruding.
The hot plate test has been the gold standard test for thermal pain tests in rodents and acts as an effective screening tool interventions of analgesia. Science Hot Plate adopt precise PID control algorithm, which is different from the temperature breakpoint method adopted by ordinary temperature controllers. The PID algorithm will continuously collect temperature feedback to control heating, thus being able to control the current temperature more accurately. The Hot Plate contains a metal temperature plate with a digital display and a lidded transparent glass cylindrical restrainer.
The small animal metabolism monitoring system has the advantages of real-time statistics, automation, and high accuracy, which greatly improves the efficiency of drug research and development and basic life science research, and fundamentally reduces the data bias and error caused by manual operation.The Metabolic Cage is used to collect and separate rodents’ urine and feces and allows measurement of their food and water intake for qualitative and quantitative studies. Short term and long-term monitoring are available. It is common use in pharmacology, pharmacodynamics, toxicology, nutrition, obesity metabolism, diabetes, cardiovascular, transgenic, geriatric disease and other research.
Rodent Electronic Von Frey/Plantar Analgesia Meter, it allows researchers to determine the mechanical pain sensitivity threshold in a simple and accurate method, through the sensitive filament stimulation. It is commonly used in screening and testing analgesic drugs, and used to determine the mechanism of central and peripheral nerve analgesia.
The Rodent Treadmill is widely used in the research of physical fitness, endurance, motor injury, motor nutraceuticals, motor physiology, pharmacology, metabolic and cardiovascular research etc. It consists of the main unit, incorporating the drive, the shocker, the control unit with 7 Inch touch screen, the running belt enclosed within a chamber constructed of acrylic and aluminum. The chamber contains a shock grid, which serves as an aversive stimulus to motivate exercise. Two sizes are available in our company, smaller size for mice and a larger size for rats.
RotaRod is mainly used for motor coordination, balance testing, anti-fatigue drug screening and identification testing, acted as the effective tool to assess motor performance in rodents using the natural fear of falling as motivation. When the rodent falls off its cylinder section on to the plate below, the rotating time and the speed of falling will be recorded.
Running wheels, or Activity Wheels, are designed to provide an easy convenient method for measuring laboratory mice or rats’ motor activity over long periods of time, data acquisition system is included. Especially useful for research on circadian rhythms, motor function, aging, energy balance, recovering and pain related exercise.The running-wheel is made of stainless steel, provided with low friction Teflon bushing, for quite smooth action. The wheel is housed in a standard clear polycarbonate cage and a stainless steel wire lid with exclusive locks fasten securely to the cage body. Our running wheel can record both the forward and reverse running data, including the number of turns, distance, running time, and the corresponding average speed in two directions respectively. The data can be collected by connecting to the software and mini-printer to record the activity of the rodents real time. Up to 24 wheels can be connected to the same counter or PC at the same time.
Sleep deprivation (SD) impairs spatial, emotional, and working memories, and augments anxiety-like behaviors. The sleep deprivation apparatus from Science is an automated device that provides movement at programmed intervals to prevent REM sleep. The apparatus consists of a clear acrylic chamber atop a motor and screen to set time and rotations of a bar inside the chamber to prevent the rodent from sleeping in a safe way. Food and water apparatuses are available to allow long-term experimentation. Our device equips with a circadian rhythm light control system, and it can be used for optogenetic experiments and calcium ion imaging experiments.
